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Nationwide, at least 45 million people ages 12 and older, or one out of five adolescents and adults, have had genital HSV infection.

HSV-1 can cause genital herpes, but it more commonly causes infections of the mouth and lips, so-called ? HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection.

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Generally, a person can only get HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection.

Transmission can occur from an infected partner who does not have a visible sore and may not know that he or she is infected.

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